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Impact of Intermittent Presumptive Treatment for Malaria in Pregnancy on Hospital Birth Outcomes on the Kenyan Coast
Author(s) -
Alice Kamau,
Moses Musau,
Stella Mwakio,
David Amadi,
Amek Nyaguara,
Philip Bejon,
Anna C. Seale,
James A. Berkley,
Robert W. Snow
Publication year - 2022
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciac509
Subject(s) - medicine , malaria , odds ratio , sulfadoxine/pyrimethamine , pregnancy , sulfadoxine , low birth weight , confidence interval , obstetrics , kenya , adverse effect , logistic regression , pediatrics , pyrimethamine , plasmodium falciparum , immunology , biology , political science , law , genetics
Intermittent preventive treatment (IPTp) for pregnant women with sulfadoxine-pyrimethamine (SP) is widely implemented for the prevention of malaria in pregnancy and adverse birth outcomes. The efficacy of SP is declining, and there are concerns that IPTp may have reduced impact in areas of high resistance. We sought to determine the protection afforded by SP as part of IPTp against adverse birth outcomes in an area with high levels of SP resistance on the Kenyan coast.

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