Real-World Incidence of Breakthrough Coronavirus Disease 2019 Hospitalization After Vaccination vs Natural Infection in a Large, Local, Empaneled Primary Care Population Using Time-to-Event Analysis | Zendy

Benjamin D. Pollock | Zendy; Curtis B. Storlie | Zendy; Aaron J. Tande | Zendy; Priya Sampathkumar | Zendy

Open Access

Real-World Incidence of Breakthrough Coronavirus Disease 2019 Hospitalization After Vaccination vs Natural Infection in a Large, Local, Empaneled Primary Care Population Using Time-to-Event Analysis

Author(s) -

Benjamin D. Pollock,

Curtis B. Storlie,

Aaron J. Tande,

Priya Sampathkumar

Publication year - 2022

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciac186

Subject(s) - medicine , incidence (geometry) , context (archaeology) , vaccination , primary care , covid-19 , coronavirus , disease , population , event (particle physics) , emergency medicine , pediatrics , intensive care medicine , infectious disease (medical specialty) , family medicine , virology , environmental health , paleontology , physics , quantum mechanics , optics , biology

We followed 106,349 primary care patients for 22,385,309 person-days across 21 calendar months. There were 69 breakthrough COVID-19 hospitalizations: 65/102,613(0.06%) among fully vaccinated, 3/11,047(0.03%) among those previously infected, and 1/7,313(0.01%) among those with both statuses. This data gives primary care providers real-world context regarding breakthrough COVID-19 hospitalization risk.

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