Validation of ISARIC 4C Mortality and Deterioration Scores in a Mixed Vaccination Status Cohort of Hospitalized Coronavirus Disease 2019 (COVID-19) Patients in Singapore | Zendy

Sean Wei Xiang Ong | Zendy; Stephanie Sutjipto | Zendy; Pei Hua Lee | Zendy; Christopher Dugan | Zendy; Bo Yan Khoo | Zendy; Dongdong Ren | Zendy; Barnaby Edward Young | Zendy; David Chien Lye | Zendy

Open Access

Validation of ISARIC 4C Mortality and Deterioration Scores in a Mixed Vaccination Status Cohort of Hospitalized Coronavirus Disease 2019 (COVID-19) Patients in Singapore

Author(s) -

Sean Wei Xiang Ong,

Stephanie Sutjipto,

Pei Hua Lee,

Christopher Dugan,

Bo Yan Khoo,

Dongdong Ren,

Barnaby Edward Young,

David Chien Lye

Publication year - 2022

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciac087

Subject(s) - medicine , cohort , covid-19 , vaccination , cohort study , receiver operating characteristic , coronavirus , disease , virology , outbreak , infectious disease (medical specialty)

In this cross-sectional study, we studied performance of the International Severe Acute Respiratory and Emerging Infections Consortium mortality and deterioration scores in a cohort of 410 hospitalized patients (51.2% fully vaccinated). area under the receiver operating characteristic curves were 0.778 and 0.764, respectively, comparable to originally published validation cohorts. Subgroup analysis showed equally good performance in vaccinated and partially or unvaccinated patients.

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