Open AccessCirculation of Third-Generation Cephalosporin Resistant Salmonella Typhi in Mumbai, India
Author(s) -
Silvia Argimón,
Geetha Nagaraj,
Varun Shamanna,
D Sravani,
Ashwini Kodlipet Vasanth,
Akshatha Prasanna,
Aruna Poojary,
Anurag Kumar Bari,
Anthony Underwood,
Mihir Kekre,
Stephen Baker,
David M. Aanensen,
Ravikumar Kadahalli Lingegowda
Publication year - 2021
Publication title -
clinical infectious diseases/clinical infectious diseases (online. university of chicago. press)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciab897
Subject(s) - salmonella typhi , cephalosporin , medicine , mutant , context (archaeology) , microbiology and biotechnology , plasmid , salmonella , virology , gene , antibiotics , biology , bacteria , genetics , escherichia coli , paleontology
We report the persistent circulation of third-generation cephalosporin resistant Salmonella Typhi in Mumbai, linked to the acquisition and maintenance of a previously characterized IncX3 plasmid carrying the ESBL gene blaSHV-12 and the fluoroquinolone resistance gene qnrB7 in the genetic context of a triple mutant also associated with fluoroquinolone resistance.