Circulation of Third-Generation Cephalosporin Resistant Salmonella Typhi in Mumbai, India
Author(s) -
Silvia Argimón,
Geetha Nagaraj,
Varun Shamanna,
D Sravani,
Ashwini Kodlipet Vasanth,
Akshatha Prasanna,
Aruna Poojary,
Anurag Kumar Bari,
Anthony Underwood,
Mihir Kekre,
Stephen Baker,
David M. Aanensen,
Ravikumar Kadahalli Lingegowda
Publication year - 2021
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciab897
Subject(s) - salmonella typhi , cephalosporin , medicine , mutant , context (archaeology) , microbiology and biotechnology , plasmid , salmonella , virology , gene , antibiotics , biology , bacteria , genetics , escherichia coli , paleontology
We report the persistent circulation of third-generation cephalosporin resistant Salmonella Typhi in Mumbai, linked to the acquisition and maintenance of a previously characterized IncX3 plasmid carrying the ESBL gene blaSHV-12 and the fluoroquinolone resistance gene qnrB7 in the genetic context of a triple mutant also associated with fluoroquinolone resistance.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom