Association of E484K Spike Protein Mutation With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Vaccinated Persons: Maryland, January–May 2021 | Zendy

Kenneth A. Feder | Zendy; Ami B. Patel | Zendy; Venkata R. Vepachedu | Zendy; Catherine Dominguez | Zendy; Eric N. Keller | Zendy; Liore Klein | Zendy; Curi Kim | Zendy; Tim Blood | Zendy; Judie Hyun | Zendy; Thelonious W. Williams | Zendy; Katherine A. Feldman | Zendy; Heba H. Mostafa | Zendy; C. Paul Morris | Zendy; Jacques Ravel | Zendy; Monique Duwell | Zendy; David Blythe | Zendy; Robert A. Myers | Zendy

Open Access

Association of E484K Spike Protein Mutation With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Vaccinated Persons: Maryland, January–May 2021

Author(s) -

Kenneth A. Feder,

Ami B. Patel,

Venkata R. Vepachedu,

Catherine Dominguez,

Eric N. Keller,

Liore Klein,

Curi Kim,

Tim Blood,

Judie Hyun,

Thelonious W. Williams,

Katherine A. Feldman,

Heba H. Mostafa,

C. Paul Morris,

Jacques Ravel,

Monique Duwell,

David Blythe,

Robert A. Myers

Publication year - 2021

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciab762

Subject(s) - medicine , covid-19 , spike protein , virology , coronavirus , vaccination , betacoronavirus , respiratory system , mutation , immunology , outbreak , biology , gene , disease , genetics , infectious disease (medical specialty)

Among 9048 people infected with SARS-CoV-2 between January and May 2021 in Maryland, in regression-adjusted analysis, SARS-CoV-2 viruses carrying the spike protein mutation E484K were disproportionately prevalent among persons infected after full vaccination against COVID-19 compared with infected persons who were not fully vaccinated (aOR, 1.96; 95% CI: 1.36–2.83).

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