Clinical Practice Guideline by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA): 2021 Focused Update Guidelines on Management of Clostridioides difficile Infection in Adults | Zendy

Stuart Johnson | Zendy; Valéry Lavergne | Zendy; Andrew M Skinner | Zendy; Anne J Gonzales-Luna | Zendy; Kevin W. Garey | Zendy; Ciarán P. Kelly | Zendy; Mark H. Wilcox | Zendy

Open Access

Clinical Practice Guideline by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA): 2021 Focused Update Guidelines on Management of Clostridioides difficile Infection in Adults

Author(s) -

Stuart Johnson,

Valéry Lavergne,

Andrew M Skinner,

Anne J Gonzales-Luna,

Kevin W. Garey,

Ciarán P. Kelly,

Mark H. Wilcox

Publication year - 2021

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciab718

Subject(s) - medicine , guideline , health care , multidisciplinary approach , epidemiology , family medicine , grading (engineering) , clinical epidemiology , medline , clostridioides , infection control , intensive care medicine , pathology , social science , civil engineering , sociology , political science , law , engineering , economics , economic growth

This clinical practice guideline is a focused update on management of Clostridioides difficile infection (CDI) in adults specifically addressing the use of fidaxomicin and bezlotoxumab for the treatment of CDI. This guideline was developed by a multidisciplinary panel representing the Infectious Diseases Society of America (IDSA) and the Society for Healthcare Epidemiology of America (SHEA). This guideline is intended for use by healthcare professionals who care for adults with CDI, including specialists in infectious diseases, gastroenterologists, hospitalists, pharmacists, and any clinicians and healthcare providers caring for these patients. The panel’s recommendations for the management CDI are based upon evidence derived from topic-specific systematic literature reviews. Summarized below are the recommendations for the management of CDI in adults. The panel followed a systematic process which included a standardized methodology for rating the certainty of the evidence and strength of recommendation using the GRADE approach (Grading of Recommendations Assessment, Development, and Evaluation). A detailed description of background, methods, evidence summary and rationale that support each recommendation, and knowledge gaps can be found online in the full text.

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