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Effect of Viral Replication and Liver Fibrosis on All-Cause Mortality in Human Immunodeficiency Virus–Hepatitis B Virus–Coinfected Individuals: A Retrospective Analysis of a 15-Year Longitudinal Cohort
Author(s) -
Lorenza N C Dezanet,
Raisha Kassime,
Patrick Miailhes,
Caroline LascouxCombe,
Julie Chas,
Sarah Maylin,
Audrey Gabassi,
Hayette Rougier,
Constance Delaugerre,
Karine Lacombe,
Anders Boyd
Publication year - 2021
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciab594
Subject(s) - medicine , viral load , hepatitis b virus , interquartile range , cumulative incidence , hepatitis b , virology , immunology , hepatitis c , gastroenterology , cohort , virus
In individuals living with human immunodeficiency virus (HIV) and hepatitis B virus (HBV), widespread tenofovir (TDF)-containing antiretroviral therapy (ART) has led to substantial decreases in HBV-DNA and HIV-RNA detection. However, the links between viral replication, liver fibrosis, and mortality remain unclear.

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