Variants of Concern Are Overrepresented Among Postvaccination Breakthrough Infections of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in Washington State | Zendy

Abbye E. McEwen | Zendy; Seth A. Cohen | Zendy; Chloe BrysonCahn | Zendy; Catherine Liu | Zendy; Steven A. Pergam | Zendy; John B. Lynch | Zendy; Adrienne Schippers | Zendy; Kathy Strand | Zendy; Estella Whimbey | Zendy; Nandita S Mani | Zendy; Allison Zelikoff | Zendy; Vanessa A Makarewicz | Zendy; Elizabeth R. Brown | Zendy; Shah A. Mohamed Bakhash | Zendy; Noah Baker | Zendy; Jared Castor | Zendy; Robert Livingston | Zendy; MeeiLi Huang | Zendy; Keith R. Jerome | Zendy; Alexander L. Greninger | Zendy; Pavitra Roychoudhury | Zendy

Open Access

Variants of Concern Are Overrepresented Among Postvaccination Breakthrough Infections of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in Washington State

Author(s) -

Abbye E. McEwen,

Seth A. Cohen,

Chloe BrysonCahn,

Catherine Liu,

Steven A. Pergam,

John B. Lynch,

Adrienne Schippers,

Kathy Strand,

Estella Whimbey,

Nandita S Mani,

Allison Zelikoff,

Vanessa A Makarewicz,

Elizabeth R. Brown,

Shah A. Mohamed Bakhash,

Noah Baker,

Jared Castor,

Robert Livingston,

MeeiLi Huang,

Keith R. Jerome,

Alexander L. Greninger,

Pavitra Roychoudhury

Publication year - 2021

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciab581

Subject(s) - medicine , covid-19 , betacoronavirus , respiratory system , virology , coronavirus , coronavirus infections , immunology , outbreak , infectious disease (medical specialty) , disease

Across 20 vaccine breakthrough cases detected at our institution, all 20 (100%) infections were due to variants of concern (VOCs) and had a median Ct of 20.2 (IQR, 17.1–23.3). When compared with 5174 contemporaneous samples sequenced in our laboratory, VOCs were significantly enriched among breakthrough infections (P < .05).

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