Circulating Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine Antigen Detected in the Plasma of mRNA-1273 Vaccine Recipients | Zendy

Alana F. Ogata | Zendy; ChiAn Cheng | Zendy; Michaël Desjardins | Zendy; Yasmeen Senussi | Zendy; Amy C Sherman | Zendy; Megan Powell | Zendy; Lewis A. Novack | Zendy; Salena S Von | Zendy; Xiaofang Li | Zendy; Lindsey R. Baden | Zendy; David R. Walt | Zendy

Open Access

Circulating Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine Antigen Detected in the Plasma of mRNA-1273 Vaccine Recipients

Author(s) -

Alana F. Ogata,

ChiAn Cheng,

Michaël Desjardins,

Yasmeen Senussi,

Amy C Sherman,

Megan Powell,

Lewis A. Novack,

Salena S Von,

Xiaofang Li,

Lindsey R. Baden,

David R. Walt

Publication year - 2021

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciab465

Subject(s) - medicine , coronavirus , covid-19 , antibody , immunology , respiratory system , virology , immunoglobulin g , severe acute respiratory syndrome coronavirus , severe acute respiratory syndrome , antigen , infectious disease (medical specialty) , disease

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) proteins were measured in longitudinal plasma samples collected from 13 participants who received two doses of mRNA-1273 vaccine. Eleven of 13 participants showed detectable levels of SARS-CoV-2 protein as early as day 1 after first vaccine injection. Clearance of detectable SARS-CoV-2 protein correlated with production of immunoglobulin G (IgG) and immunoglobulin A (IgA).

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