Evaluating the Diagnostic Test Accuracy of Molecular Xenomonitoring Methods for Characterizing Community Burden of Lymphatic Filariasis | Zendy

Joseph Pryce | Zendy; Lisa J. Reimer | Zendy

Open Access

Evaluating the Diagnostic Test Accuracy of Molecular Xenomonitoring Methods for Characterizing Community Burden of Lymphatic Filariasis

Author(s) -

Joseph Pryce,

Lisa J. Reimer

Publication year - 2021

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciab197

Subject(s) - lymphatic filariasis , medicine , confidence interval , mass drug administration , microfilaria , prevalence , filariasis , veterinary medicine , immunology , epidemiology , population , environmental health , helminths

Molecular xenomonitoring (MX), the detection of pathogen DNA in mosquitoes, is a recommended approach to support lymphatic filariasis (LF) elimination efforts. Potential roles of MX include detecting presence of LF in communities and quantifying progress towards elimination of the disease. However, the relationship between MX results and human prevalence is poorly understood.

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