Waning Vaccine Effectiveness Against Influenza-Associated Hospitalizations Among Adults, 2015–2016 to 2018–2019, United States Hospitalized Adult Influenza Vaccine Effectiveness Network | Zendy

Jill M. Ferdinands | Zendy; Manjusha Gaglani | Zendy; Emily T. Martin | Zendy; Arnold S. Monto | Zendy; Donald B. Middleton | Zendy; Fernanda P. Silveira | Zendy; H. Keipp Talbot | Zendy; Richard K. Zimmerman | Zendy; Manish M. Patel | Zendy

Open Access

Waning Vaccine Effectiveness Against Influenza-Associated Hospitalizations Among Adults, 2015–2016 to 2018–2019, United States Hospitalized Adult Influenza Vaccine Effectiveness Network

Author(s) -

Jill M. Ferdinands,

Manjusha Gaglani,

Emily T. Martin,

Arnold S. Monto,

Donald B. Middleton,

Fernanda P. Silveira,

H. Keipp Talbot,

Richard K. Zimmerman,

Manish M. Patel

Publication year - 2021

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciab045

Subject(s) - medicine , vaccination , influenza vaccine , live attenuated influenza vaccine , virology , immunology , pediatrics

We observed decreased effectiveness of influenza vaccine with increasing time since vaccination for prevention of influenza A(H3N2), influenza A(H1N1)pdm09, and influenza B/Yamagata–associated hospitalizations among adults. Maximum vaccine effectiveness (VE) was observed shortly after vaccination, followed by an absolute decline in VE of about 8%–9% per month postvaccination.

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