Infections in Patients Colonized With Extended-spectrum Beta-Lactamase-Producing Enterobacterales: A Retrospective Cohort Study | Zendy

Isabelle Vock | Zendy; Lisandra AguilarBultet | Zendy; Adrian Egli | Zendy; Pranita D. Tamma | Zendy; Sarah TschudinSutter | Zendy

Open Access

Infections in Patients Colonized With Extended-spectrum Beta-Lactamase-Producing Enterobacterales: A Retrospective Cohort Study

Author(s) -

Isabelle Vock,

Lisandra AguilarBultet,

Adrian Egli,

Pranita D. Tamma,

Sarah TschudinSutter

Publication year - 2020

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciaa895

Subject(s) - medicine , beta lactamase , retrospective cohort study , cohort , biology , escherichia coli , biochemistry , gene

We investigated relative proportions of extended-spectrum beta-lactamase-producing Enterobacterales (ESBL-PE) versus non-ESBL-PE (nESBL-PE) infections in ESBL-PE colonized patients. ESBL-PE are not causative for the majority of infections in hospitalized patients colonized with ESBL-PE. Site of infection and patient-level exposures may be useful predictors of nESBL-PE infections, potentially guiding empiric treatment recommendations.

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