Performance of Oropharyngeal Swab Testing Compared With Nasopharyngeal Swab Testing for Diagnosis of Coronavirus Disease 2019—United States, January 2020–February 2020 | Zendy

Monita R. Patel | Zendy; Darin S. Carroll | Zendy; Emily N. Ussery | Zendy; Hilary K. Whitham | Zendy; Christopher A. Elkins | Zendy; Judith NobleWang | Zendy; J. Kamile Rasheed | Zendy; Xiaoyan Lu | Zendy; Stephen Lindstrom | Zendy; Virginia B. Bowen | Zendy; Jessica L. Waller | Zendy; Gregory L. Armstrong | Zendy; Susan I. Gerber | Zendy; John T. Brooks | Zendy

Open Access

Performance of Oropharyngeal Swab Testing Compared With Nasopharyngeal Swab Testing for Diagnosis of Coronavirus Disease 2019—United States, January 2020–February 2020

Author(s) -

Monita R. Patel,

Darin S. Carroll,

Emily N. Ussery,

Hilary K. Whitham,

Christopher A. Elkins,

Judith NobleWang,

J. Kamile Rasheed,

Xiaoyan Lu,

Stephen Lindstrom,

Virginia B. Bowen,

Jessica L. Waller,

Gregory L. Armstrong,

Susan I. Gerber,

John T. Brooks

Publication year - 2020

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciaa759

Subject(s) - medicine , covid-19 , coronavirus , virology , polymerase chain reaction , diagnostic test , betacoronavirus , disease , biology , veterinary medicine , infectious disease (medical specialty) , outbreak , gene , biochemistry

Among 146 nasopharyngeal (NP) and oropharyngeal (OP) swab pairs collected ≤7 days after illness onset, Real-Time Reverse Transcriptase Polymerase Chain Reaction assay for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 RT-PCR) diagnostic results were 95.2% concordant. However, NP swab cycle threshold values were lower (indicating more virus) in 66.7% of concordant-positive pairs, suggesting NP swabs may more accurately detect the amount of SARS-CoV-2.

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