Occurrence and Timing of Subsequent Severe Acute Respiratory Syndrome Coronavirus 2 Reverse-transcription Polymerase Chain Reaction Positivity Among Initially Negative Patients | Zendy

Dustin R. Long | Zendy; Saurabh Gombar | Zendy; Catherine A. Hogan | Zendy; Alexander L. Greninger | Zendy; Vikas N. O’Reilly-Shah | Zendy; Chloe BrysonCahn | Zendy; Bryan Stevens | Zendy; Arjun Rustagi | Zendy; Keith R. Jerome | Zendy; Christina S. Kong | Zendy; James L. Zehnder | Zendy; Nigam H. Shah | Zendy; Noel S. Weiss | Zendy; Benjamin A. Pinsky | Zendy; Jacob E. Sunshine | Zendy

Open Access

Occurrence and Timing of Subsequent Severe Acute Respiratory Syndrome Coronavirus 2 Reverse-transcription Polymerase Chain Reaction Positivity Among Initially Negative Patients

Author(s) -

Dustin R. Long,

Saurabh Gombar,

Catherine A. Hogan,

Alexander L. Greninger,

Vikas N. O’Reilly-Shah,

Chloe BrysonCahn,

Bryan Stevens,

Arjun Rustagi,

Keith R. Jerome,

Christina S. Kong,

James L. Zehnder,

Nigam H. Shah,

Noel S. Weiss,

Benjamin A. Pinsky,

Jacob E. Sunshine

Publication year - 2020

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciaa722

Subject(s) - medicine , reverse transcription polymerase chain reaction , polymerase chain reaction , coronavirus , reverse transcriptase , respiratory system , covid-19 , immunology , virology , disease , gene , infectious disease (medical specialty) , biology , messenger rna , genetics

Using data for 20,912 patients from two large academic health systems, we analyzed the frequency of SARS-CoV-2 RT-PCR test-discordance among individuals initially testing negative by nasopharyngeal swab who were retested on clinical grounds within 7 days. The frequency of subsequent positivity within this window was 3.5% and similar across institutions.

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