Open AccessPrevalence of Immunoglobulin G (IgG) Against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and Evaluation of a Rapid MEDsan IgG Test in Children Seeking Medical Care
Author(s) -
Klara M. PosfayBarbe,
Diego O. Andrey,
Julien Virzi,
Patrick Cohen,
Fiona Pigny,
Ana Rita Gonçalves,
Selina Pinösch,
Laurence Lacroix,
Silvia Stringhini,
Laurent Kaiser,
Nicolas Vuilleumier,
Arnaud G. L’Huillier
Publication year - 2020
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciaa1702
Subject(s) - covid-19 , medicine , immunoglobulin g , coronavirus , antibody , virology , immunology , severe acute respiratory syndrome coronavirus , respiratory system , outbreak , infectious disease (medical specialty) , disease
In 208 children seeking medical care, the seropositivity rate of anti–SARS-CoV-2 IgG antibodies was 8.7%, suggesting an infection rate similar to that observed in adults but >100-fold the incidence of RT-PCR–confirmed pediatric cases. Compared with the gold-standard combined ELISA + immunofluorescence, the MEDsan IgG rapid diagnostic test performed accurately.
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