“SILVAMP TB LAM” Rapid Urine Tuberculosis Test Predicts Mortality in Patients Hospitalized With Human Immunodeficiency Virus in South Africa | Zendy

Bianca Sossen | Zendy; Tobias Broger | Zendy; Andrew D. Kerkhoff | Zendy; Charlotte Schutz | Zendy; André Trollip | Zendy; Emmanuel Moreau | Zendy; Samuel G. Schumacher | Zendy; Rosie Burton | Zendy; Amy Ward | Zendy; Robert J. Wilkinson | Zendy; David Barr | Zendy; Mark P. Nicol | Zendy; Claudia M. Denkinger | Zendy; Graeme Meintjes | Zendy

Open Access

“SILVAMP TB LAM” Rapid Urine Tuberculosis Test Predicts Mortality in Patients Hospitalized With Human Immunodeficiency Virus in South Africa

Author(s) -

Bianca Sossen,

Tobias Broger,

Andrew D. Kerkhoff,

Charlotte Schutz,

André Trollip,

Emmanuel Moreau,

Samuel G. Schumacher,

Rosie Burton,

Amy Ward,

Robert J. Wilkinson,

David Barr,

Mark P. Nicol,

Claudia M. Denkinger,

Graeme Meintjes

Publication year - 2020

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciaa024

Subject(s) - tuberculosis , medicine , human immunodeficiency virus (hiv) , urine , retrospective cohort study , pediatrics , virology , pathology

Reducing diagnostic delay is key toward decreasing tuberculosis-associated deaths in people living with human immunodeficiency virus. In tuberculosis patients with retrospective urine testing, the point-of-care Fujifilm SILVAMP TB LAM (FujiLAM) could have rapidly diagnosed tuberculosis in up to 89% who died. In FujiLAM negative patients, the probability of 12-week survival was 86-97%.

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