Maternal Dietary Choline Status Influences Brain Gray and White Matter Development in Young Pigs | Zendy

Austin T. Mudd | Zendy; Caitlyn M Getty | Zendy; Ryan N. Dilger | Zendy

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Maternal Dietary Choline Status Influences Brain Gray and White Matter Development in Young Pigs

Author(s) -

Austin T. Mudd,

Caitlyn M Getty,

Ryan N. Dilger

Publication year - 2018

Publication title -

current developments in nutrition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.904

H-Index - 14

ISSN - 2475-2991

DOI - 10.1093/cdn/nzy015

Subject(s) - choline , white matter , colostrum , lactation , physiology , medicine , endocrinology , biology , pregnancy , magnetic resonance imaging , radiology , genetics , antibody , immunology

Observations from this study suggest that prenatal choline deficiency results in altered cortical gray matter and reduced white matter in the internal capsule and putamen of young pigs. With the use of noninvasive neuroimaging techniques, results from our study indicate that prenatal choline deficiency greatly alters gray and white matter development in pigs, thereby providing a translational assessment that may be used in clinical populations.

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