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Magnetoencephalography imaging of high frequency oscillations strengthens presurgical localization and outcome prediction
Author(s) -
J Velmurugan,
Srikantan S. Nagarajan,
N. Mariyappa,
Ravindranadh Chowdary Mundlamuri,
Raghavendra Kenchaiah,
Rose Dawn Bharath,
Jitender Saini,
Arimappamagan Arivazhagan,
Jamuna Rajeswaran,
Anita Mahadevan,
Bhaskara Rao Malla,
Parthasarathy Satishchandra,
Sanjib Sinha
Publication year - 2019
Publication title -
brain
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.142
H-Index - 336
eISSN - 1460-2156
pISSN - 0006-8950
DOI - 10.1093/brain/awz284
Subject(s) - magnetoencephalography , outcome (game theory) , epilepsy , epilepsy surgery , psychology , neuroscience , medicine , electroencephalography , mathematics , mathematical economics
See van Klink and Zijlmans (doi:10.1093/brain/awz321) for a scientific commentary on this article. Velmuruganet al. report that detecting and localizing high‐frequency oscillations (HFOs: 80–200 Hz) with MEG can improve presurgical assessment and postsurgical outcome prediction in epilepsy. Source localization of HFOs identifies an epileptogenic region with accuracy of 75%. When such localized sources are surgically resected, patients have an approximately 80% probability of achieving seizure freedom.

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