Reply: Does dominant pedunculopontine nucleus exist? Probably not

Sir,We are pleased to continue the discussion with regards to our recent manuscript detailing altered structural connectivity of the locomotor network within the right hemisphere of individuals with Parkinson’s disease who experience freezing of gait (Fling et al. , 2013). Our previous work has asserted the possibility of right hemisphere pathology as a principal neural component underlying freezing of gait, with an emphasis placed on disrupted communication between locomotor centres in the brainstem and cerebellum with medial areas of the frontal and prefrontal cortices (Fling et al. , 2013, 2014 a ). In their letter to the editor, Hall and colleagues (2014) provide data demonstrating that freezing of gait is evident in Parkinson's disease regardless of which side of the body is more affected. The authors report no difference in the proportion of subjects ( n = …