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1 Neuromuscular Diseases Research Section, Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD 20892, USA 2 Computational Biology Core, Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD 20892, USA 3 Molecular Genetics Section, Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD 20892, USA 4 Neurological Institute, Catholic University and Insieme Contro le Malattie del Motoneurone Association for ALS Research, Largo Agostino Gemelli 8, Rome 00168, Italy 5 Molecular Genetics Unit, Department of Clinical Pathology, Azienda Sanitaria Ospedaliera Ospedale Infantile Regina Margherita-Santa Anna, Turin 10126, Italy 6 Department of Neurology, Sourasky Medical Centre, 6 Weizmann Street, Tel Aviv 64239, Israel 7 ‘Rita Levi Montalcini’ Department of Neuroscience, University of Turin, Turin 10124, Italy 8 Tanz Centre for Research of Neurodegenerative Diseases, Division of Neurology, Department of Medicine, University of Toronto, Toronto, Ontario M5S 3H2, Canada

Mutations in the CHCHD10 gene are a common cause of familial amyotrophic lateral sclerosis