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Small fibre neuropathy, fibromyalgia and dorsal root ganglia sodium channels
Author(s) -
Manuel MartínezLavin
Publication year - 2013
Publication title -
brain
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.142
H-Index - 336
eISSN - 1460-2156
pISSN - 0006-8950
DOI - 10.1093/brain/awt114
Subject(s) - fibromyalgia , neuropathic pain , medicine , peripheral neuropathy , fibromyalgia syndrome , dorsal root ganglion , sensory system , nociception , dorsum , physical medicine and rehabilitation , anesthesia , physical therapy , neuroscience , psychology , anatomy , endocrinology , diabetes mellitus , receptor
ARTICLESir,In their elegant study, Uceyler et al. (2013) provide objective evidence of small fibre neuropathy in patients with fibromyalgia. They conclude that fibromyalgia may be a neuropathic pain syndrome (Uceyler et al. , 2013). Small fibre neuropathy is a disorder of the peripheral nerves resulting in sensory changes and sympathetic dysfunction.For years, we have proposed that fibromyalgia is a neuropathic pain syndrome based on the following three arguments: (i) fibromyalgia is a stimulus-independent pain state. There is no structural damage that could explain the pain …

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