Open AccessReply: The cerebellum in Parkinson’s disease and parkinsonism in cerebellar disorders
Author(s) -
Tao Wu,
Mark Hallett
Publication year - 2013
Publication title -
brain
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.142
H-Index - 336
eISSN - 1460-2156
pISSN - 0006-8950
DOI - 10.1093/brain/awt100
Subject(s) - parkinsonism , cerebellum , parkinson's disease , neuroscience , cerebellar diseases , cerebellar ataxia , medicine , degenerative disease , psychology , disease , central nervous system disease , pathology , ataxia
ARTICLESir,We thank Pedroso et al. (2013) for their interest in our paper (Wu and Hallett, 2013), in which we discussed the role of the cerebellum in Parkinson’s disease; other types of parkinsonism were not included. Such parkinsonian disorders often contain overt pathological changes in both basal ganglia and cerebellar systems. The origin of these changes is generally thought to be primary in both locations, but it is conceivable that the primary pathology is in one location and secondary in the other. It is important to recognize that genetic mutations can cause different phenotypes and that the nomenclature …
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