Open AccessReply to: can CBT substantially change grey matter volume in chronic fatigue syndrome?
Author(s) -
Floris P. de Lange,
A. Koers,
Joke S. Kalkman,
Gijs Bleijenberg,
Peter Hagoort,
J.W.M. van der Meer,
Ivan Toni
Publication year - 2008
Publication title -
brain
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.142
H-Index - 336
eISSN - 1460-2156
pISSN - 0006-8950
DOI - 10.1093/brain/awn208
Subject(s) - chronic fatigue syndrome , grey matter , psychology , volume (thermodynamics) , medicine , physical medicine and rehabilitation , psychiatry , magnetic resonance imaging , white matter , radiology , physics , quantum mechanics
Sir, We thank Dr Bramsen for her interest in our recently published article (de Lange et al. 2008). In this article, we report on an increase in prefrontal grey matter volume following cognitive behavioural therapy (CBT) in a group of patients suffering from the chronic fatigue syndrome (CFS).Dr Bramsen raises two points of criticism. First, she questions the lack of a control group of patients receiving no treatment or a different treatment. While this limitation was already emphasized in the discussion section of de Lange et al. (2008), it remains unclear how the observed behavioral and cerebral changes could be accounted for by generic and CBT-independent factors. Dr …
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