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Sir, To correlate magnetic resonance imaging (MRI) patterns with tissue destruction is interesting, but to correlate MR patterns with ongoing inflammation to predict the fate of a lesion is of great importance in clinical practice of Multiple sclerosis (MS). The paper of Nessler et al. (2007) reporting early and predictive MRI changes in a mouse model of MS is therefore of great interest. The paper …

MRI to predict severe tissue damage in inflammatory lesions in animal models of multiple sclerosis