Targeting human PPN: few patients, numerous disputes | Zendy

Alessandro Stefani | Zendy; Andrés M. Lozano | Zendy; Paolo Stanzione | Zendy; P. Mazzone | Zendy

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Targeting human PPN: few patients, numerous disputes

Author(s) -

Alessandro Stefani,

Andrés M. Lozano,

Paolo Stanzione,

P. Mazzone

Publication year - 2007

Publication title -

brain

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.142

H-Index - 336

eISSN - 1460-2156

pISSN - 0006-8950

DOI - 10.1093/brain/awm139

Subject(s) - subthalamic nucleus , pedunculopontine nucleus , neuroscience , parkinson's disease , psychology , medicine , philosophy , disease , deep brain stimulation , pathology

Sir, Dr Yelnik highlights an important issue, already extensively addressed (consider Mazzone et al ., 2007 a , b in response to Zrinzo and co-authors). Briefly, there is no doubt that some figures were misleading (Stefani et al ., 2007). In describing our original approach to the first six Parkinson's disease (PD) patients double-implanted in the subthalamic nucleus (STN) plus the pedunculopontine nucleus (PPN), we have emphasized the trajectory through …

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