Impaired theta phase coupling underlies frontotemporal dysconnectivity in schizophrenia | Zendy

Rick A. Adams | Zendy; Daniel Bush | Zendy; Fanfan Zheng | Zendy; Sofie S. Meyer | Zendy; Raphael Kaplan | Zendy; Stelios Orfanos | Zendy; Tiago Reis Marques | Zendy; Oliver Howes | Zendy; Neil Burgess | Zendy

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Impaired theta phase coupling underlies frontotemporal dysconnectivity in schizophrenia

Author(s) -

Rick A. Adams,

Daniel Bush,

Fanfan Zheng,

Sofie S. Meyer,

Raphael Kaplan,

Stelios Orfanos,

Tiago Reis Marques,

Oliver Howes,

Neil Burgess

Publication year - 2020

Publication title -

brain

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.142

H-Index - 336

eISSN - 1460-2156

pISSN - 0006-8950

DOI - 10.1093/brain/awaa035

Subject(s) - neuroscience , schizophrenia (object oriented programming) , psychology , frontotemporal dementia , coupling (piping) , physics , medicine , psychiatry , materials science , dementia , disease , pathology , metallurgy

Communication between the frontal and medial temporal lobes is impaired in schizophrenia. Adams et al . find that when retrieving memories, subjects with schizophrenia have lower theta phase oscillatory coupling between these areas, and lower α-GABA A receptor availability in the hippocampal area where coupling is lost.

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