Open AccessApoptosis and rotator cuff tears: scientific evidence from basic science to clinical findings
Author(s) -
Leonardo Osti,
Matteo Buda,
Angelo Del Buono,
Raffaella Osti,
Leo Massari,
Nicola Maffulli
Publication year - 2017
Publication title -
british medical bulletin
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.08
H-Index - 112
eISSN - 1471-8391
pISSN - 0007-1420
DOI - 10.1093/bmb/ldx008
Subject(s) - tendinopathy , rotator cuff , tears , medicine , apoptosis , tendon , bioinformatics , surgery , pathology , biology , biochemistry
Excessive apoptosis has been hypothesized as possible cause of tendinopathy and tear in the tendons of the rotator cuff (RC). Different mechanisms and molecules play a key role in cell regulation. Biological interventions can affect the process of apoptosis to control the tendinopathy process, and may be useful to design new treatments.
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