F-18 FDG PET/CT imaging of cardiac and vascular inflammation and infection | Zendy

Ismaheel O. Lawal | Zendy; Mike Sathekge | Zendy

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F-18 FDG PET/CT imaging of cardiac and vascular inflammation and infection

Author(s) -

Ismaheel O. Lawal,

Mike Sathekge

Publication year - 2016

Publication title -

british medical bulletin

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.08

H-Index - 112

eISSN - 1471-8391

pISSN - 0007-1420

DOI - 10.1093/bmb/ldw035

Subject(s) - medicine , inflammation , positron emission tomography , cardiac imaging , disease , pet ct , radiology , pathology

Inflammation forms an important core of the aetiopathogenic process involved in many diseases affecting the heart and the blood vessels. These diseases include infections as well as inflammatory non-infectious cardiovascular conditions. The common feature of this is invasion of the heart or blood vessel by inflammatory cells. F-18 2-fluoro 2-deoxy-D glucose (FDG) is an analogue of glucose and like glucose it is taken up by activated inflammatory cells that accumulate at the site of infection. This has formed the basis of the use of F-18 FDG PET/CT in the non-invasive evaluation of human inflammatory diseases.

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