EP.TU.947Rectosigmoid Cancer Resection in a District General Hospital – A single centre experience

Aims To identify common factors amongst patients who had undergone rectosigmoid cancer resections Materials & Methods This is a single centre retrospective study including patients who underwent recto-sigmoid cancer resections by a senior colo-rectal surgeon from year 2012 to 2018. Patients’ data were identified through a local trust database. Patients’ variables were subjected to Mann Whitney, Chi Square analysis and survival function plots. Results Of the 102 patients, we observed a mean age of 66 years with a slight male sex predisposition(58%) . Two-thirds were referred through the 2 week-wait GP pathway with predominant symptoms being bleeding and change in bowel habits (70 and 60% respectively). Male sex was associated with longer length of stay (LoS), younger age at surgery, higher T-staging and tumour size. Patients who had laparoscopic surgery converted to open and those with stoma had the longest LoS. Histological results of higher Dukes, T and N stage were associated with higher patient mortality rates. Advanced N and Dukes staging were also related to higher propensity of disease recurrence with new metastases. In those with positive circumferential resection margin (CRM) on histology, there were higher correlation with local and distal disease recurrences as well as higher post-op mortality rate (all the above had p-values <0.05). Conclusion The factors identified in previous large scale studies do correlate with our experience in a district general hospital and identification of sub-groups of patients at higher risk of adverse outcomes can be identified in further studies.