Applying an intraoperative predictive indicator for postoperative pancreatic fistula: randomized preclinical trial | Zendy

Thomas Pausch | Zendy; Clara Mitzscherling | Zendy; Ophelia Aubert | Zendy; Xinchun Liu | Zendy; Bodil Gesslein | Zendy; Thomas Brückner | Zendy; F. Kommoss | Zendy; Mohammad Golriz | Zendy; Arianeb Mehrabi | Zendy; Thilo Hackert | Zendy

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Applying an intraoperative predictive indicator for postoperative pancreatic fistula: randomized preclinical trial

Author(s) -

Thomas Pausch,

Clara Mitzscherling,

Ophelia Aubert,

Xinchun Liu,

Bodil Gesslein,

Thomas Brückner,

F. Kommoss,

Mohammad Golriz,

Arianeb Mehrabi,

Thilo Hackert

Publication year - 2021

Publication title -

british journal of surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.202

H-Index - 201

eISSN - 1365-2168

pISSN - 0007-1323

DOI - 10.1093/bjs/znaa115

Subject(s) - medicine , pancreatic fistula , randomized controlled trial , leak , clinical trial , surgery , general surgery , pancreas , environmental engineering , engineering

Leaking pancreatic fluid can contribute to postoperative pancreatic fistula (POPF), which can complicate pancreatic surgery. Surgeons lack reliable tools to identify pancreatic leaks, so a novel hydrogel indicator called SmartPAN was developed for intraoperative application. In this preclinical efficacy assessment study, SmartPAN was capable of detecting sites associated with biochemical leak and POPF-related symptoms, thereby guiding effective closure. Thus, SmartPAN may help to reduce POPF development in upcoming clinical trials.

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