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Learning complex subcellular distribution patterns of proteins via analysis of immunohistochemistry images
Author(s) -
Yingying Xu,
HongBin Shen,
Robert F. Murphy
Publication year - 2019
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btz844
Subject(s) - human protein atlas , subcellular localization , proteomics , protein subcellular localization prediction , computer science , source code , computational biology , similarity (geometry) , biology , pattern recognition (psychology) , protein expression , artificial intelligence , cytoplasm , image (mathematics) , gene , biochemistry , operating system
Systematic and comprehensive analysis of protein subcellular location as a critical part of proteomics ('location proteomics') has been studied for many years, but annotating protein subcellular locations and understanding variation of the location patterns across various cell types and states is still challenging.

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