CircaCompare: a method to estimate and statistically support differences in mesor, amplitude and phase, between circadian rhythms | Zendy

Rex Parsons | Zendy; Richard Parsons | Zendy; Nicholas Garner | Zendy; Henrik Oster | Zendy; Oliver Rawashdeh | Zendy

Open Access

CircaCompare: a method to estimate and statistically support differences in mesor, amplitude and phase, between circadian rhythms

Author(s) -

Rex Parsons,

Richard Parsons,

Nicholas Garner,

Henrik Oster,

Oliver Rawashdeh

Publication year - 2019

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btz730

Subject(s) - circadian rhythm , amplitude , rhythm , phase (matter) , statistics , biology , endocrinology , mathematics , medicine , chemistry , physics , quantum mechanics , organic chemistry

A fundamental interest in chronobiology is to compare patterns between groups of rhythmic data. However, many existing methods are ill-equipped to derive statements concerning the statistical significance of differences between rhythms that may be visually apparent. This is attributed to both the form of data used (longitudinal versus cross-sectional) and the limitations of the statistical tests used to draw conclusions.

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