Zombi: a phylogenetic simulator of trees, genomes and sequences that accounts for dead linages
Author(s) -
Adrián Davín,
Théo Tricou,
Éric Tannier,
Damien M. de Vienne,
Gergely J. Szöllősi
Publication year - 2019
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btz710
Subject(s) - phylogenetic tree , tree (set theory) , genome , computer science , source code , code (set theory) , biology , gene , genetics , programming language , mathematics , mathematical analysis , set (abstract data type)
Here we present Zombi, a tool to simulate the evolution of species, genomes and sequences in silico, that considers for the first time the evolution of genomes in extinct lineages. It also incorporates various features that have not to date been combined in a single simulator, such as the possibility of generating species trees with a pre-defined variation of speciation and extinction rates through time, simulating explicitly intergenic sequences of variable length and outputting gene tree-species tree reconciliations.
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