hypeR: an R package for geneset enrichment workflows
Author(s) -
Anthony Federico,
Stefano Monti
Publication year - 2019
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btz700
Subject(s) - workflow , computer science , r package , visualization , flexibility (engineering) , throughput , range (aeronautics) , data mining , data science , software engineering , database , operating system , programming language , statistics , mathematics , wireless , materials science , composite material
Geneset enrichment is a popular method for annotating high-throughput sequencing data. Existing tools fall short in providing the flexibility to tackle the varied challenges researchers face in such analyses, particularly when analyzing many signatures across multiple experiments. We present a comprehensive R package for geneset enrichment workflows that offers multiple enrichment, visualization, and sharing methods in addition to novel features such as hierarchical geneset analysis and built-in markdown reporting. hypeR is a one-stop solution to performing geneset enrichment for a wide audience and range of use cases.
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