XMAn v2—a database of Homo sapiens mutated peptides
Author(s) -
Marcela Aguilera Flores,
Iulia M. Lazar
Publication year - 2019
Publication title -
bioinformatics
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btz693
Subject(s) - sequence database , homo sapiens , nonsense mutation , tandem mass spectrometry , computational biology , missense mutation , identification (biology) , nonsense , computer science , database search engine , sequence (biology) , protein sequencing , peptide sequence , mutation , genetics , database , biology , mass spectrometry , gene , information retrieval , chemistry , search engine , botany , chromatography , sociology , anthropology
The 'Unknown Mutation Analysis (XMAn)' database is a compilation of Homo sapiens mutated peptides in FASTA format, that was constructed for facilitating the identification of protein sequence alterations by tandem mass spectrometry detection. The database comprises 2 539 031 non-redundant mutated entries from 17 599 proteins, of which 2 377 103 are missense and 161 928 are nonsense mutations. It can be used in conjunction with search engines that seek the identification of peptide amino acid sequences by matching experimental tandem mass spectrometry data to theoretical sequences from a database.
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