Cram-JS: reference-based decompression in node and the browser | Zendy

Robert Buels | Zendy; Shihab Dider | Zendy; Colin Diesh | Zendy; James Robinson | Zendy; Ian Holmes | Zendy

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Cram-JS: reference-based decompression in node and the browser

Author(s) -

Robert Buels,

Shihab Dider,

Colin Diesh,

James Robinson,

Ian Holmes

Publication year - 2019

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btz384

Subject(s) - javascript , computer science , huffman coding , node (physics) , world wide web , source code , operating system , information retrieval , data compression , artificial intelligence , structural engineering , engineering

The CRAM format addresses rising DNA storage costs for short-read sequencing by aligning reads to a reference genome and encoding the resulting alignment with Huffman, subexponential, Elias gamma, rANS, gzip and other codes. The CRAM codec is complex, and until now, there has been no JavaScript implementation.

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