Open AccessRNA-align: quick and accurate alignment of RNA 3D structures based on size-independent TM-scoreRNA
Author(s) -
Sha Gong,
Chengxin Zhang,
Yang Zhang
Publication year - 2019
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btz282
Subject(s) - rna , computer science , computational biology , genetics , biology , gene
Comparison of RNA 3D structures can be used to infer functional relationship of RNA molecules. Most of the current RNA structure alignment programs are built on size-dependent scales, which complicate the interpretation of structure and functional relations. Meanwhile, the low speed prevents the programs from being applied to large-scale RNA structural database search.
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