phylostratr: a framework for phylostratigraphy | Zendy

Zebulun Arendsee | Zendy; Jing Li | Zendy; Urminder Singh | Zendy; Arun S. Seetharam | Zendy; Karin S. Dorman | Zendy; Eve Syrkin Wurtele | Zendy

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phylostratr: a framework for phylostratigraphy

Author(s) -

Zebulun Arendsee,

Jing Li,

Urminder Singh,

Arun S. Seetharam,

Karin S. Dorman,

Eve Syrkin Wurtele

Publication year - 2019

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btz171

Subject(s) - clade , uniprot , inference , computer science , genome , source code , computational biology , homology (biology) , tree (set theory) , gene prediction , gene , biology , data mining , genetics , artificial intelligence , phylogenetics , programming language , mathematical analysis , mathematics

The goal of phylostratigraphy is to infer the evolutionary origin of each gene in an organism. This is done by searching for homologs within increasingly broad clades. The deepest clade that contains a homolog of the protein(s) encoded by a gene is that gene's phylostratum.

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