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Assembly Graph Browser: interactive visualization of assembly graphs
Author(s) -
Alla Mikheenko,
Mikhail Kolmogorov
Publication year - 2019
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btz072
Subject(s) - visualization , computer science , graph drawing , graph layout , contig , interactive visualization , graph , sequence assembly , theoretical computer science , genome , data mining , biology , biochemistry , gene expression , transcriptome , gene
Currently, most genome assembly projects focus on contigs and scaffolds rather than assembly graphs that provide a more comprehensive representation of an assembly. Since interactive visualization of large assembly graphs remains an open problem, we developed an Assembly Graph Browser (AGB) tool that visualizes large assembly graphs, extending the functionality of previously developed visualization approaches. Assembly Graph Browser includes a number of novel functions including repeat analysis, construction of the contracted assembly graphs (i.e. the graphs obtained by collapsing a selected set of edges) and a new approach to visualizing large assembly graphs.

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