Computational modeling of cellular structures using conditional deep generative networks | Zendy

Hao Yuan | Zendy; Lei Cai | Zendy; Zhengyang Wang | Zendy; Xia Hu | Zendy; Shaoting Zhang | Zendy; Shuiwang Ji | Zendy

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Computational modeling of cellular structures using conditional deep generative networks

Author(s) -

Hao Yuan,

Lei Cai,

Zhengyang Wang,

Xia Hu,

Shaoting Zhang,

Shuiwang Ji

Publication year - 2018

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/bty923

Subject(s) - computer science , generative grammar , artificial intelligence , theoretical computer science , machine learning , algorithm

Cellular function is closely related to the localizations of its sub-structures. It is, however, challenging to experimentally label all sub-cellular structures simultaneously in the same cell. This raises the need of building a computational model to learn the relationships among these sub-cellular structures and use reference structures to infer the localizations of other structures.

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