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A Bayesian model for single cell transcript expression analysis on MERFISH data
Author(s) -
Johannes Köster,
Myles Brown,
X. Shirley Liu
Publication year - 2018
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/bty718
Subject(s) - computer science , bayesian probability , workflow , computational biology , expression (computer science) , data mining , raw data , multiplexing , algorithm , biology , artificial intelligence , database , programming language , telecommunications
Multiplexed error-robust fluorescence in-situ hybridization (MERFISH) is a recent technology to obtain spatially resolved gene or transcript expression profiles in single cells for hundreds to thousands of genes in parallel. So far, no statistical framework to analyze MERFISH data is available.

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