JustOrthologs: a fast, accurate and user-friendly ortholog identification algorithm | Zendy

Justin Miller | Zendy; Brandon D. Pickett | Zendy; Perry G. Ridge | Zendy

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JustOrthologs: a fast, accurate and user-friendly ortholog identification algorithm

Author(s) -

Justin Miller,

Brandon D. Pickett,

Perry G. Ridge

Publication year - 2018

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/bty669

Subject(s) - identification (biology) , genome , gene , computational biology , biology , phylogenetic tree , source code , computer science , pairwise comparison , genetics , artificial intelligence , botany , operating system

Orthologous gene identification is fundamental to all aspects of biology. For example, ortholog identification between species can provide functional insights for genes of unknown function and is a necessary step in phylogenetic inference. Currently, most ortholog identification algorithms require all-versus-all BLAST comparisons, which are time-consuming and memory intensive.

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