ACDtool: a web-server for the generic analysis of large data sets of counts | Zendy

JeanMichel Claverie | Zendy; Thi Ngan Ta | Zendy

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ACDtool: a web-server for the generic analysis of large data sets of counts

Author(s) -

JeanMichel Claverie,

Thi Ngan Ta

Publication year - 2018

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/bty640

Subject(s) - pairwise comparison , computer science , interface (matter) , data mining , information retrieval , artificial intelligence , bubble , parallel computing , maximum bubble pressure method

More than 20 years ago, our laboratory published an original statistical test [referred to as the Audic-Claverie (AC) test in the literature] to identify differentially expressed genes from the pairwise comparison of counts of 'expressed sequence tags' determined in different conditions. Despite its antiquity and the publications of more sophisticated packages, this original publication continued to gather more than 200 citations per year, indicating the persistent usefulness of the simple AC test for the community. This prompted us to propose a fully revamped version of the AC test with a user interface adapted to the diverse and much larger datasets produced by contemporary omics techniques.

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