CNEFinder: finding conserved non-coding elements in genomes | Zendy

Lorraine A. K. Ayad | Zendy; Solon P. Pissis | Zendy; Dimitris Polychronopoulos | Zendy

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CNEFinder: finding conserved non-coding elements in genomes

Author(s) -

Lorraine A. K. Ayad,

Solon P. Pissis,

Dimitris Polychronopoulos

Publication year - 2018

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/bty601

Subject(s) - genome , computational biology , conserved sequence , coding (social sciences) , computer science , biology , genetics , base sequence , gene , mathematics , statistics

Conserved non-coding elements (CNEs) represent an enigmatic class of genomic elements which, despite being extremely conserved across evolution, do not encode for proteins. Their functions are still largely unknown. Thus, there exists a need to systematically investigate their roles in genomes. Towards this direction, identifying sets of CNEs in a wide range of organisms is an important first step. Currently, there are no tools published in the literature for systematically identifying CNEs in genomes.

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