htsget: a protocol for securely streaming genomic data
Author(s) -
Jerome Kelleher,
Mike C. Lin,
C H Albach,
Ewan Birney,
Robert M. Davies,
Marina Gourtovaia,
David Glazer,
Cristina González,
David K. Jackson,
Aaron S. Kemp,
John Marshall,
Andrew Nowak,
Alexander Senf,
Jaime M. Tovar-Corona,
Alexander Vikhorev,
Thomas Keane,
Dixie B. Baker,
Vadim Zalunin,
Angel Pizarro,
Richard Durbin,
Mark Diekhans,
Edmon Begoli,
Ilia Tulchinsky,
Heng Li,
Rishi Nag,
Stephen Keenan,
Ilkka Lappalainen,
Jim Robinson
Publication year - 2018
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/bty492
Subject(s) - computer science , protocol (science) , computer network , medicine , pathology , alternative medicine
Standardized interfaces for efficiently accessing high-throughput sequencing data are a fundamental requirement for large-scale genomic data sharing. We have developed htsget, a protocol for secure, efficient and reliable access to sequencing read and variation data. We demonstrate four independent client and server implementations, and the results of a comprehensive interoperability demonstration.
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