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Recombinational DSBs-intersected genes converge on specific disease- and adaptability-related pathways
Author(s) -
Zhikai Yang,
Hao Luo,
Yanming Zhang,
Baijing Wang,
Feng Gao
Publication year - 2018
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/bty376
Subject(s) - biology , saccharomyces cerevisiae , adaptability , recombination , genetics , population , gene , genome , homologous recombination , computational biology , range (aeronautics) , ecology , demography , materials science , sociology , composite material
The budding yeast Saccharomyces cerevisiae is a model species powerful for studying the recombination of eukaryotes. Although many recombination studies have been performed for this species by experimental methods, the population genomic study based on bioinformatics analyses is urgently needed to greatly increase the range and accuracy of recombination detection. Here, we carry out the population genomic analysis of recombination in S.cerevisiae to reveal the potential rules between recombination and evolution in eukaryotes.

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