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REGGAE: a novel approach for the identification of key transcriptional regulators
Author(s) -
Tim Kehl,
Lara Schneider,
Kathrin Kattler,
Daniel Stöckel,
Jenny Wegert,
Nico Gerstner,
Nicole Ludwig,
Ute Distler,
Markus Schick,
Ulrich Keller,
Stefan Tenzer,
Manfred Gessler,
Jörn Walter,
Andreas Keller,
Norbert Graf,
Eckart Meese,
HansPeter Lenhof
Publication year - 2018
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/bty372
Subject(s) - identification (biology) , key (lock) , computational biology , computer science , biology , computer security , ecology
Transcriptional regulators play a major role in most biological processes. Alterations in their activities are associated with a variety of diseases and in particular with tumor development and progression. Hence, it is important to assess the effects of deregulated regulators on pathological processes.

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