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The UEA sRNA Workbench (version 4.4): a comprehensive suite of tools for analyzing miRNAs and sRNAs
Author(s) -
M. B. Stocks,
Irina Mohorianu,
Matthew Beckers,
Claudia Paicu,
Simon Moxon,
Joshua Thody,
Tamás Dalmay,
Vincent Moulton
Publication year - 2018
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/bty338
Subject(s) - workbench , suite , computer science , microrna , computational biology , software , biology , data mining , genetics , operating system , gene , geography , visualization , archaeology
RNA interference, a highly conserved regulatory mechanism, is mediated via small RNAs (sRNA). Recent technical advances enabled the analysis of larger, complex datasets and the investigation of microRNAs and the less known small interfering RNAs. However, the size and intricacy of current data requires a comprehensive set of tools, able to discriminate the patterns from the low-level, noise-like, variation; numerous and varied suggestions from the community represent an invaluable source of ideas for future tools, the ability of the community to contribute to this software is essential.

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