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FaStore: a space-saving solution for raw sequencing data
Author(s) -
Łukasz Roguski,
Idoia Ochoa,
Mikel Hernáez,
Sebastian Deorowicz
Publication year - 2018
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/bty205
Subject(s) - lossy compression , lossless compression , computer science , data compression , compression ratio , raw data , data mining , compression (physics) , encoding (memory) , computer engineering , algorithm , artificial intelligence , engineering , materials science , automotive engineering , composite material , programming language , internal combustion engine
The affordability of DNA sequencing has led to the generation of unprecedented volumes of raw sequencing data. These data must be stored, processed and transmitted, which poses significant challenges. To facilitate this effort, we introduce FaStore, a specialized compressor for FASTQ files. FaStore does not use any reference sequences for compression and permits the user to choose from several lossy modes to improve the overall compression ratio, depending on the specific needs.

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