CarbonylDB: a curated data-resource of protein carbonylation sites | Zendy

R. Shyama Prasad Rao | Zendy; Ning Zhang | Zendy; Dong Xu | Zendy; Ian Max Møller | Zendy

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CarbonylDB: a curated data-resource of protein carbonylation sites

Author(s) -

R. Shyama Prasad Rao,

Ning Zhang,

Dong Xu,

Ian Max Møller

Publication year - 2018

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/bty123

Subject(s) - protein carbonylation , carbonylation , oxidative stress , biomarker , oxidative phosphorylation , computational biology , resource (disambiguation) , biology , bioinformatics , biochemistry , oxidative damage , computer science , computer network , carbon monoxide , catalysis

Oxidative stress and protein damage have been associated with over 200 human ailments including cancer, stroke, neuro-degenerative diseases and aging. Protein carbonylation, a chemically diverse oxidative post-translational modification, is widely considered as the biomarker for oxidative stress and protein damage. Despite their importance and extensive studies, no database/resource on carbonylated proteins/sites exists. As such information is very useful to research in biology/medicine, we have manually curated a data-resource (CarbonylDB) of experimentally-confirmed carbonylated proteins/sites.

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